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Koeppe nodules- čvorići

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Pridružen: 18-06-2008 14:05
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Lokacija: Zagreb
http://dro.hs.columbia.edu/irisnodules.htm

Two types of iris nodules can develop in granulomatous uveitis. When situated at the pupillary margin (and on the surface of the iris) they are called Koeppe nodules, have a fluffy appearance and a size going from very small barely visible excresences to frank nodules. When situated in the body of the iris stroma, iris nodules are called Bussaca nodules.

Koeppe nodules (inflammatory cell precipitates which lie at the pupillary margin and could be found in non-granulomaous as well as granulomatous uveitis). Koeppe nodules occur on the iris sphincter margin and commonly are seen in Fuchs heterochromic iridocyclitis without synechiae formation.
Koeppe nodules can be seen in HLA-B27 disease, herpetic infections, and any granulomatous uveitis.

Bussaca nodules (lie on the iris surface) which are pathognomonic for granulomatous uveitis.
When the inflammation is treated, the nodules will resolve.
Busacca nodules occur within the iris stroma and generally are accompanied by even more severe inflammation; therefore, they are less common than Koeppe nodules. These are seen with granulomatous uveitis and never with nongranulomatous uveitis; hence, they are valuable diagnostically.


http://www.ncbi.nlm.nih.gov/pmc/article ... 3-0065.pdf

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